Investigators looking for answers in the shooting death of a woman in Santee

Shirley Isaac

Shirley Isaac
Source: Midlands Crimestoppers (Image provided by family)

COLUMBIA, SC (WOLO)– Investigators with Midlands Crimestoppers and the Orangeburg County Sheriff’s Office are asking for information about the shooting death of a 43-year-old woman at a residence on Resort Street in Santee. Around 4:30 a.m. on February 20, authorities say Shirley Isaac was killed as a result of being shot. Investigators say there were several other adults and children at the residence at the time, and one child suffered serious injuries after being shot.

Anyone with information about this incident should call Crimestoppers at 1-888-CRIMES-SC or submit a tip online to

Categories: Local News, Orangeburg